Aminocaproic Acid (Oral Route)

    Aminocaproic Acid (Oral Route)

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    Description and Brand Names of Aminocaproic Acid (Oral Route)

    US Brand Name

    1. Amicar

    Descriptions

    Aminocaproic acid is an antifibrinolytic agent. It is used to treat serious bleeding conditions, especially when the bleeding occurs after dental surgery or other kinds of surgery. This medicine is also sometimes given before an operation to prevent serious bleeding for patients with medical problems that increase the chance of bleeding.

    This medicine is available only with your doctor’s prescription.

    This product is available in the following dosage forms:

    • Solution
    • Syrup
    • Tablet

    Before Using Aminocaproic Acid (Oral Route)

    In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

    Allergies

    Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

    Pediatric

    Appropriate studies have not been performed on the relationship of age to the effects of aminocaproic acid in the pediatric population. Safety and efficacy have not been established.

    Geriatric

    No information is available on the relationship of age to the effects of aminocaproic acid in geriatric patients.

    Pregnancy

    Breastfeeding

    There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

    Drug Interactions

    Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

    Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

    • Anti-Inhibitor Coagulant Complex
    • Tretinoin

    Other Interactions

    Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

    Other Medical Problems

    The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

    • Blood clots, active or
    • Disseminated intravascular coagulation or DIC (blood clotting problem) – Should not be used in patients with these conditions.
    • Blood clots, history of or
    • Hematuria (blood in the urine) – Use with caution. May make these conditions worse.
    • Kidney disease – The effects of this medicine may be increased because of slower removal of the medicine from the body.

    Proper Use of Aminocaproic Acid (Oral Route)

    Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

    Measure the oral solution with a marked measuring spoon, oral syringe, or medicine cup.

    Dosing

    The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

    The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

    • To treat bleeding problems:

      • For oral dosage form (solution or tablets):

        • Adults – 5 grams (g) or 4 teaspoonfuls as a single dose for the first hour, followed by 1 g or 1 teaspoonful every hour for 8 hours or until bleeding has been controlled.
        • Children – Use and dose must be determined by your doctor.

    Missed Dose

    This medicine needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions.

    Storage

    Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

    Keep out of the reach of children.

    Do not keep outdated medicine or medicine no longer needed.

    Ask your healthcare professional how you should dispose of any medicine you do not use.

    Precautions

    It is very important that your doctor check your progress while you are using this medicine. Blood tests may be needed to see if the medicine is working properly and to check for unwanted effects.

    Using this medicine for a long time may cause muscle problems and serious kidney disease. Check with your doctor right away if you have a dark-colored urine; fever; joint pain; muscle cramps or spasms; or unusual tiredness or weakness.

    Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

    Side Effects of Aminocaproic Acid (Oral Route)

    Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

    Check with your doctor immediately if any of the following side effects occur:

    Incidence not known

    1. Anxiety
    2. black, tarry stools
    3. bleeding gums
    4. blood in the urine or stools
    5. blurred vision
    6. change in the ability to see colors, especially blue or yellow
    7. chest pain or discomfort
    8. chills
    9. confusion
    10. cough or hoarseness
    11. dark-colored urine
    12. decreased frequency or amount of urine
    13. difficult or labored breathing
    14. difficulty with moving
    15. difficulty with speaking
    16. difficulty with swallowing
    17. dizziness or lightheadedness
    18. dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
    19. double vision
    20. fainting
    21. fast heartbeat
    22. fever with or without chills
    23. general feeling of discomfort or illness
    24. general feeling of tiredness or weakness
    25. headache
    26. hives
    27. inability to move the arms, legs, or facial muscles
    28. inability to speak
    29. increased thirst
    30. itching of the skin
    31. joint pain
    32. loss of appetite
    33. lower back or side pain
    34. muscle aching or cramping
    35. muscle cramps or spasms
    36. muscle pain or stiffness
    37. muscular pain, tenderness, wasting, or weakness
    38. nausea and vomiting
    39. numbness and tingling of the face, fingers, or toes
    40. pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion
    41. painful or difficult urination
    42. pale, bluish-colored, or cold hands or feet
    43. pinpoint red spots on the skin
    44. problems with bleeding or clotting
    45. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    46. shortness of breath
    47. skin rash
    48. slow or irregular heartbeat
    49. slow speech
    50. sore throat
    51. sores, ulcers, or white spots on the lips or in the mouth
    52. sudden shortness of breath or troubled breathing sweating
    53. swelling
    54. swelling of the face, fingers, or lower legs
    55. swollen glands
    56. swollen joints
    57. tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
    58. tightness in the chest
    59. troubled breathing
    60. unusual bleeding or bruising
    61. unusual tiredness or weakness
    62. vomiting
    63. weak or absent pulses in the legs
    64. weight gain
    65. wheezing

    Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

    Incidence not known

    1. Abdominal or stomach pain
    2. confusion as to time, place, or person
    3. continuing ringing or buzzing or other unexplained noise in the ears
    4. decreased vision
    5. diarrhea
    6. ejaculation without semen
    7. hearing loss
    8. holding false beliefs that cannot be changed by fact
    9. mood or mental changes
    10. seeing, hearing, or feeling things that are not there
    11. stuffy nose
    12. unusual excitement, nervousness, or restlessness
    13. watery eyes

    Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

    Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.