Home Legionellosis (Legionnaires' disease)

    Legionellosis (Legionnaires’ disease)


    Definition of Legionellosis (Legionnaires’ disease)

    Legionnaires’ disease is a severe form of pneumonia — lung inflammation usually caused by infection. Legionnaires’ disease is caused by a bacterium known as legionella.

    You can’t catch Legionnaires’ disease from person-to-person contact. Instead, most people get Legionnaires’ disease from inhaling the bacteria. Older adults, smokers and people with weakened immune systems are particularly susceptible to Legionnaires’ disease.

    The legionella bacterium also causes Pontiac fever, a milder illness resembling the flu. Separately or together, the two illnesses are sometimes called legionellosis. Pontiac fever usually clears on its own, but untreated Legionnaires’ disease can be fatal. Although prompt treatment with antibiotics usually cures Legionnaires’ disease, some people continue to experience problems after treatment.

    Symptoms of Legionellosis (Legionnaires’ disease)

    Legionnaires’ disease usually develops two to 10 days after exposure to legionella bacteria. It frequently begins with the following signs and symptoms:

    • Headache
    • Muscle pain
    • Chills
    • Fever that may be 104 F (40 C) or higher

    By the second or third day, you’ll develop other signs and symptoms that may include:

    • Cough, which may bring up mucus and sometimes blood
    • Shortness of breath
    • Chest pain
    • Gastrointestinal symptoms, such as nausea, vomiting and diarrhea
    • Confusion or other mental changes

    Although Legionnaires’ disease primarily affects the lungs, it occasionally can cause infections in wounds and in other parts of the body, including the heart.

    A mild form of Legionnaires’ disease — known as Pontiac fever — may produce signs and symptoms including fever, chills, headache and muscle aches. Pontiac fever doesn’t infect your lungs, and symptoms usually clear within two to five days.

    When to see a doctor

    See your doctor if you think you’ve been exposed to legionella bacteria. Diagnosing and treating Legionnaires’ disease as soon as possible can help shorten the recovery period and prevent serious complications. For people at high risk, prompt treatment is critical.


    The bacterium Legionella pneumophila is responsible for most cases of Legionnaires’ disease. Outdoors, legionella bacteria survive in soil and water, but rarely cause infections. Indoors, though, legionella bacteria can multiply in all kinds of water systems — hot tubs, air conditioners and mist sprayers in grocery store produce departments.

    Although it’s possible to contract Legionnaires’ disease from home plumbing systems, most outbreaks have occurred in large buildings, perhaps because complex systems allow the bacteria to grow and spread more easily.

    How the infection spreads

    Most people become infected when they inhale microscopic water droplets containing legionella bacteria. This might be the spray from a shower, faucet or whirlpool, or water dispersed through the ventilation system in a large building. Outbreaks have been linked to a range of sources, including:

    • Hot tubs and whirlpools on cruise ships
    • Cooling towers in air conditioning systems
    • Decorative fountains
    • Swimming pools
    • Physical therapy equipment
    • Water systems in hotels, hospitals and nursing homes

    Although legionella bacteria primarily spread through aerosolized water droplets, the infection can be transmitted in other ways, including:

    • Aspiration. This occurs when liquids accidentally enter your lungs, usually because you cough or choke while drinking. If you aspirate water containing legionella bacteria, you may develop Legionnaires’ disease.
    • Soil. A few people have contracted Legionnaires’ disease after working in the garden or using contaminated potting soil.

    Risk factors

    Not everyone exposed to legionella bacteria becomes sick. You’re more likely to develop the infection if you:

    • Smoke. Smoking damages the lungs, making you more susceptible to all types of lung infections.
    • Have a weakened immune system as a result of HIV/AIDS or certain medications, especially corticosteroids and drugs taken to prevent organ rejection after a transplant.
    • Have a chronic lung disease such as emphysema or another serious condition such as diabetes, kidney disease or cancer.
    • Are 50 years of age or older.

    Legionnaires’ disease is a sporadic and local problem in hospitals and nursing homes, where germs may spread easily and people are vulnerable to infection.

    Complications of Legionellosis (Legionnaires’ disease)

    Legionnaires’ disease can lead to a number of life-threatening complications, including:

    • Respiratory failure. This occurs when the lungs are no longer able to provide the body with enough oxygen or can’t remove enough carbon dioxide from the blood.
    • Septic shock. This occurs when a severe, sudden drop in blood pressure reduces blood flow to vital organs, especially to the kidneys and brain. The heart tries to compensate by increasing the volume of blood pumped, but the extra workload eventually weakens the heart and reduces blood flow even further.
    • Acute kidney failure. This is the sudden loss of your kidneys’ ability to perform their main function — filtering waste material from your blood. When your kidneys fail, dangerous levels of fluid and waste accumulate in your body.

    When not treated effectively and promptly, Legionnaires’ disease may be fatal, especially if your immune system is weakened by disease or medications.

    Preparing for your appointment

    You’re likely to start by seeing your family doctor or a primary care provider. However, in some cases, you may be referred to a doctor who specializes in treating lung disease (pulmonologist) or infectious diseases, or you may be advised to go to an emergency department.

    What you can do

    • Write down key information about your illness, including all the symptoms you’re experiencing. Record your temperature.
    • Tell your doctor if you’ve recently been away from home and where you stayed. If anyone you regularly associate with has an illness similar to yours, mention that to your doctor as well.
    • Write down personal information, including recent hospitalizations.
    • Make a list of all medications, vitamins and supplements you’re taking.
    • Bring a family member or friend along, if possible. Someone who goes with you may help you remember the information your doctor provides.
    • Write down questions to ask your doctor.

    Questions you might ask your doctor include:

    • What is likely causing my symptoms?
    • What are other possible causes?
    • What tests do I need?
    • What is the best course of action?
    • What are the alternatives to the approach you’re suggesting?
    • I have other health conditions. How will this illness affect them?
    • Is it possible to avoid hospitalization? If not, how many days will I be hospitalized?

    Don’t hesitate to ask any other questions you have.

    What to expect from your doctor

    Your doctor is likely to ask you a number of questions, including:

    • When did you begin experiencing symptoms?
    • Have your symptoms been continuous?
    • Have your symptoms been worsening since their onset?
    • What, if anything, seems to improve your symptoms?
    • What, if anything, appears to worsen your symptoms?

    What you can do in the meantime

    To keep from making your condition worse, follow these tips:

    • Don’t smoke or be around smoke.
    • Don’t drink alcohol.
    • Stay out of work or school, and rest as much as you can.
    • Drink plenty of fluids.

    If you get sicker before you see a doctor, go to an emergency room.

    Tests and diagnosis

    Legionnaires’ disease is similar to other types of pneumonia. To help identify the presence of legionella bacteria quickly, your doctor may use a test that checks your urine for legionella antigens — foreign substances that trigger an immune system response. You may also have one or more of the following:

    • Blood tests
    • Chest X-ray, which doesn’t confirm Legionnaires’ disease but can show the extent of infection in your lungs
    • Tests on a sample of your sputum or lung tissue
    • A CT scan of your brain or a spinal tap (lumbar puncture) if you have neurological symptoms such as confusion or trouble concentrating

    Treatments and drugs

    Legionnaires’ disease is treated with antibiotics. The sooner therapy is started, the less likely the chance of serious complications or death. In many cases, treatment requires hospitalization. Pontiac fever goes away on its own without treatment and causes no lingering problems.


    Outbreaks of Legionnaire’s disease are preventable, but prevention requires meticulous cleaning and disinfection of water systems, pools and spas.

    Avoiding smoking is the single most important thing you can do to lower your risk of infection. Smoking increases the chances that you’ll develop Legionnaires’ disease if you’re exposed to legionella bacteria.

    SOURCEMayo Clinic
    Previous articleTemporal lobe seizure
    Next articleNeuromyelitis optica